Quality of Ampicillin Preparations on the Kenyan Market

  • F N Kamau Drug Analysis Research Unit, Department of Pharmaceutical Chemistry, University of Nairobi, P.O. Box 19676 Nairobi E-mail daru@uonbi.ac.ke
  • G N Thoithi Drug Analysis Research Unit, Department of Pharmaceutical Chemistry, University of Nairobi, P.O. Box 19676 Nairobi E-mail daru@uonbi.ac.ke
  • I O Kibwage Drug Analysis Research Unit, Department of Pharmaceutical Chemistry, University of Nairobi, P.O. Box 19676 Nairobi E-mail daru@uonbi.ac.ke
Keywords: Ampicillin, formulations, pH and quality.

Abstract

Ampicillin products, 20 capsules, 2 tablets and 23 dry suspensions were evaluated for quality by liquid chromatography at the Drug Analysis Research Unit University of Nairobi. Four capsule formulations failed limits on content. The Ampicillin content in 5 suspensions dropped below 80% on storage at 25°C for 7 days. The pH of most suspensions dropped on storage, but had no correlation to decrease in chemical content.

Published
2020-07-08
How to Cite
Kamau, F., Thoithi, G., & Kibwage, I. (2020). Quality of Ampicillin Preparations on the Kenyan Market. The East and Central African Journal of Pharmaceutical Sciences, 4(1), 25-28. Retrieved from https://uonjournals.uonbi.ac.ke/ojs/index.php/ecajps/article/view/462
Issue
Vol 4 No 1 (2001): January-April 2001
Section
Articles