Quality of Antiretroviral Drugs Analyzed in the Drug Analysis and Research Unit During 2000-2003

  • K O Abuga Department of Pharmaceutical Chemistry, University of Nairobi
  • P M Mwagiru Department of Pharmaceutical Chemistry, University of Nairobi
  • G N Thoithi Department of Pharmaceutical Chemistry, University of Nairobi
  • J M Nguyo Department of Pharmaceutical Chemistry, University of Nairobi
  • J K Ngugi Department of Pharmaceutical Chemistry, University of Nairobi
  • O K King'ondu Department of Pharmaceutical Chemistry, University of Nairobi
  • H N Mugo Department of Pharmaceutical Chemistry, University of Nairobi
  • I O Kibwage Department of Pharmaceutical Chemistry, University of Nairobi
Keywords: Antiretroviral, assay, dissolution, nucleoside reverse-transcriptase inhibitor

Abstract

During the period 2000-2003 the Drug Analysis and Research Unit received and
analyzed 33 samples of antiretroviral drugs. Locally manufactured products
accounted for 57.6 % of the samples, while the imported drugs constituted 42.4
%. The drugs consisted of single, double and triple component preparations.
They were subjected to the identity, assay and dissolution tests. 30 samples (90.9
%) complied with compendial specifications for these tests, while 3 failed. The
results obtained show that manufacture of quality generic antiretroviral drugs is
achievable.

Published
2020-05-21
How to Cite
Abuga, K., Mwagiru, P., Thoithi, G., Nguyo, J., Ngugi, J., King’ondu, O., Mugo, H., & Kibwage, I. (2020). Quality of Antiretroviral Drugs Analyzed in the Drug Analysis and Research Unit During 2000-2003. The East and Central African Journal of Pharmaceutical Sciences, 6(1), 20-23. Retrieved from https://uonjournals.uonbi.ac.ke/ojs/index.php/ecajps/article/view/363
Issue
Vol 6 No 1 (2003): January-April 2003
Section
Articles