Phytosterols from Dombeya torrida (J. F. Gmel.)

  • S. N. NDWIGAH
  • G. N. THOITHI
  • J. W. MWANGI
  • B. K. AMUGUNE
  • H. N. MUGO
  • I. O. KIBWAGE
Keywords: Dombeya torrida, friedelin, friedelan-3β-ol, β-sitosterol, stigmasterol, taraxerol

Abstract

Dombeya torrida collected from Kinale forest in Kiambu County, Kenya, was Soxhlet extracted with chloroform and by percolation using a dichloromethane:methanol mixture. The extracts were fractionated using normal phase silica gel in an open column. Five compounds were isolated namely friedelin, friedelan-3β-ol, β-sitosterol, taraxerol and stigmasterol. This is the first report of isolation of these compounds from Dombeya torrida. The isolated compounds were identified by means of 1H-NMR, 13CNMR, DEPT, MS and IR analyses.

Published
2018-11-21
How to Cite
NDWIGAH, S., THOITHI, G., MWANGI, J., AMUGUNE, B., MUGO, H., & KIBWAGE, I. (2018). Phytosterols from Dombeya torrida (J. F. Gmel.). The East and Central African Journal of Pharmaceutical Sciences, 16(2), 44-48. Retrieved from https://uonjournals.uonbi.ac.ke/ojs/index.php/ecajps/article/view/152