Brine Shrimp Lethality of Alkaloids from Croton sylvaticus Hoechst
Keywords:
Croton sylvaticus, Euphorbiaceae, julocrotine, lupeol, penduliflaworosin, brine shrimp lethality
Abstract
Three compounds were isolated from the leaves of Croton sylvaticus (Euphorbiaceae) and evaluated for their brine shrimp lethality. Julocrotine, a glutarimide alkaloid, was very toxic in vitro with a LC50 (95% confidence interval) value of 0.074 (0.052-0.105) µg/ml. Lupeol and penduliflaworosin were not toxic. The structures of the isolated compounds were determined by spectroscopic methods.
Published
2018-11-21
How to Cite
KAPINGU, M., MBWAMBO, Z., MOSHI, M., & MAGADULA, J. (2018). Brine Shrimp Lethality of Alkaloids from Croton sylvaticus Hoechst. The East and Central African Journal of Pharmaceutical Sciences, 15(2), 35-37. Retrieved from https://uonjournals.uonbi.ac.ke/ojs/index.php/ecajps/article/view/137
Section
Articles
