TY - JOUR AU - Arthur Nderitu AU - Peter Karimi AU - Eric Guantai AU - Apollo Maima PY - 2021/04/19 Y2 - 2024/03/29 TI - Determinants of Adherence to Tuberculosis Chemotherapy in Nairobi City County, Kenya JF - The East and Central African Journal of Pharmaceutical Sciences JA - ECAJPS VL - 23 IS - 3 SE - Articles DO - UR - https://uonjournals.uonbi.ac.ke/ojs/index.php/ecajps/article/view/717 AB - Tuberculosis (TB) is a leading global cause of death and Kenya is among the top20 countries with a high burden of the disease. Adherence to drugs used to treatthe disease remains a crucial challenge towards the elimination of TB in Kenya.This study evaluated the rate and determinants of adherence to TB chemotherapyamong adult patients attending health clinics in Nairobi between April and May2017. A cross-sectional study was carried out in five randomly selected healthcentres in the Eastlands area of Nairobi involving 113 respondents whovoluntarily consented and met the inclusion criteria. Data was collected using aresearcher-administered questionnaire and the level of adherence assessed usingparticipants self-reporting. From the results obtained, the participants exhibitedlow (11, 9.7%), medium (46, 40.7%), and high (56, 49.6%) adherence to TBtherapy. Upon stepwise multivariate regression, the absence of a DOT supporter(p=0.039) and being on other medications (p=0.021) were significantly associatedwith non-adherence. It is inferred that DOT support enhanced adherence whileco-morbidities decreased it. ER -